I am all set to go, Wed at 1 pm for my Intralipid infusion. I am excited and nervous all at the same time. I can't wait to get this cycle moving! =)
What are Intralipids?
Hopefully part of the crazy cocktail that will give us a THB!
Intralipids Reduce NK cell activation - calm down overactive immune system/inflammation. (to help keep body from rejecting or attacking the embryo)
http://www.ncbi.nlm.nih.gov/pubmed/18782287 As effective as IVIg http://www.ncbi.nlm.nih.gov/pubmed/17362387 Intralipids are safer than IVIg as they do not contain any blood products. ILs are also around 10x cheaper than IVIg. More information: Intralipid (IL), is a synthetic product composed of 10% soybean oil, 1,2% egg yolk phospholipids, 2.25% glycerin and water. Based on research performed at SIRM and elsewhere, infusion of IL lowers Natural Killer cell activation (Nka) as effectively as does, intravenous gammaglobulin (IVIG.) When indicated IL (as with IVIG) is infused 7-10 days prior to ET and one more time again after a positive pregnancy in women whose Nka is due to an autoimmune causes (antiphospholipid antibodies and/or antithyroid antibodies). In cases of alloimmune implantation dysfunction (DQa and/ HLA matching between the embryo recipient and the male partner) the same applies but in this situation the infusion is repeated at 2-4 week intervals until the 24th week of pregnancy. We have supplanted IVIG with IL therapy in a significant number of women undergoing IVF , and who had immunologic embryo implantation dysfunction. The results thus far have been excellent, way beyond our initial expectations. At last we now have a safe and inexpensive alternative to IVIG therapy...Intralipid! What is more, IL costs about 10 times less than IVIG, is not a blood product and is without significant side effects. http://haveababy.com/sirm-innovations/immunologic-treatment.html
What are Intralipids?
Hopefully part of the crazy cocktail that will give us a THB!
Intralipids Reduce NK cell activation - calm down overactive immune system/inflammation. (to help keep body from rejecting or attacking the embryo)
http://www.ncbi.nlm.nih.gov/pubmed/18782287 As effective as IVIg http://www.ncbi.nlm.nih.gov/pubmed/17362387 Intralipids are safer than IVIg as they do not contain any blood products. ILs are also around 10x cheaper than IVIg. More information: Intralipid (IL), is a synthetic product composed of 10% soybean oil, 1,2% egg yolk phospholipids, 2.25% glycerin and water. Based on research performed at SIRM and elsewhere, infusion of IL lowers Natural Killer cell activation (Nka) as effectively as does, intravenous gammaglobulin (IVIG.) When indicated IL (as with IVIG) is infused 7-10 days prior to ET and one more time again after a positive pregnancy in women whose Nka is due to an autoimmune causes (antiphospholipid antibodies and/or antithyroid antibodies). In cases of alloimmune implantation dysfunction (DQa and/ HLA matching between the embryo recipient and the male partner) the same applies but in this situation the infusion is repeated at 2-4 week intervals until the 24th week of pregnancy. We have supplanted IVIG with IL therapy in a significant number of women undergoing IVF , and who had immunologic embryo implantation dysfunction. The results thus far have been excellent, way beyond our initial expectations. At last we now have a safe and inexpensive alternative to IVIG therapy...Intralipid! What is more, IL costs about 10 times less than IVIG, is not a blood product and is without significant side effects. http://haveababy.com/sirm-innovations/immunologic-treatment.html
I'm praying this is just what you need. You've been through too much to not come out of this journey with your rainbow! Thoughts & prayers always :)
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